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In this report, we test this hypothesis by treating the HRAS G12V -transformed ovarian epithelial cells, mutant KRAS -harboring pancreatic and colon cancer cells of mouse and human origins, as well as cancer xenografts, with diphenyleneiodonium (DPI) and buthionine sulfoximine (BSO) combination, which inhibit NOX activity and glutathione biosynthesis, respectively
Grumont R, Lock P, Mollinari M, Shannon FM, Moore A, Gerondakis S
Isothiocyanates inhibit cell cycle progression of HeLa cells at G2/M phase
