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doi: 10.3389/fnut.2024.1427608 Received 04 May 2024 Accepted 29 July 2024 Published 09 August 2024 Volume 11 - 2024 Edited by Juliana Vaz, Federal University of Pelotas, Brazil Reviewed by Jordan Maximillian Wilkins, Mayo Clinic, United States Marcelo Muniz, Federal University of Espirito Santo, Brazil Updates Copyright 2024 Singh, Hu, Singh, Solanki, Vijayaraghavan, Srivastav, Joshi, Kumari, Singh, Wang and Kumar

It plays an integral role in a number of bodily functions, including DNA production and the formation and maintenance of red blood cells and nerve cells

Eur Rev Med Pharmacol Sci 22:804259 Donato JA, Mercurio F, Karin M (2012) NF-B and the link between inflammation and cancer

Even with pharmacological developments, existing therapies such as corticosteroids, antimalarials, and immunosuppressants do not cure the disease and can have side effects like metabolic imbalances, osteoporosis, and cardiovascular involvement

Janku F, Vibat CRT, Falchook GS, Huang HJ, Hong DS, Piha-Paul SA, Subbiah V, Ramzanali NM, Hancock S, Naing A, DaKarp DD, Nitti G, Cabrilo G, Luthra R, Patel SP, Overman MJ, Kopetz S , Erlander MG, Melnikova V, Meric-Bernstam F