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In Figure 9(a), the simulation results indicate that glutathione (GSH) concentration varies significantly in the presence of oxidative stress due to the GMO (the log-scale version of this figure is in Figure B3 of Appendix B)

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10.1016/j.exger.2018.08.009 102

Library size distribution was measured with the Agilent High Sensitivity D5000 assay (Agilent) on a TapeStation 4200 (Agilent) system

Subcellular localization of GPx and change of the glutathione system during aging In view of its role in the regulation of the cellular redox status, GSH has specific vital functions within the intracellular organelles where it is located
