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These enzymes frequently require additional co-substrates or mediators that may limit their practical use for the decontamination of aflatoxins in food

As previously explained, selenoproteins, particularly GPX and TXNRD, can reduce ROS thus helping to maintain the balance (Reference Guillin, Vindry and Ohlmann14)

Leurs, R., Bakker, R

Notably, the hepsin / mice exhibited a more pronounced increase in ROS levels after thioacetamide treatment compared with wild-type mice, which aligned with our hypothesis that hepsin / mice experience heightened ROS stress in the early stages of APAP exposure due to their elevated expression of GJ proteins (Fig