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It is worth noting that studies reported that hypoxiadriven stabilization of HIF1 enhances Gln metabolism by upregulating glutaminase expression and Gln transporter activity, thereby supporting redox homeostasis and cell survival under lowoxygen stress

Instead of the old term of non-alcoholic fatty liver disease (NAFLD), a more reasonable broader substitute, metabolic dysfunction-associated steatotic liver disease (MASLD), became the spotlight because it can cover huge and diverse causes of steatosis under its umbrella (Rinella et al

O(2)(-) and H(2)O(2)-mediated disruption of Fe metabolism causes the differential susceptibility of NSCLC and GBM cancer cells to pharmacological ascorbate
