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Common Symptoms of a Vitamin B12 Deficiency If you think you may be low, watch out for these symptoms: Feeling tired, fatigue and weakness Loss of appetite Constipation Weight loss Megaloblastic anemia Numbness and tingling Poor balance or coordination Confusion Memory loss Depression (21) Soreness of mouth and/or tongue (22) Be aware that many symptoms of B12 deficiency overlap with symptoms of other health conditions, so it's important to see your doctor for a definitive diagnosis

Reversible dissociation of -glutamylcysteine synthetase into two subunits

That does not prove anything about Dihexa's subjective effects in healthy users, but it is the relevant clinical context and the reason no validated human timeline exists