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Our results demonstrated that the co-treatment of 3-BP and cetuximab synergistically induced an antiproliferative effect in both CRC cell lines with intrinsic cetuximab resistance (DLD-1 (KRAS G13D/- ) and HT29 (BRAF V600E )) and in a cetuximab-resistant cell line derived from Caco-2 with acquired resistance (Caco-2-CR)

Early research has explored its use alongside treatment for depression and neurodegenerative conditions

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up to 70% of fALS cases are majorly attributed to four genes: C9orf72, SOD1, TARDBP, and FUS (29), while other ALS-causing genes and their roles are enlisted in Table 2