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Enhancing antioxidant defenses through dietary intake, pharmacological agents, or upregulation of endogenous antioxidant systems offers a promising strategy to protect the BBB and combat the deleterious effects of oxidative stress in the CNS [27,38,143]

2,97 The EFSA also states that B12 has not been found to be carcinogenic or mutagenic in in vitro and in vivo studies

PMID: 31674171

[DOI] [PubMed] [Google Scholar] Gao X.H., Bedhomme M., Michelet M., Zaffagnini M., Lemaire S.D