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The goal is to maintain a steady level of pain relief so you never hit that painful crash. By alternating the medications every 3 hours (each individual drug taken every 6 hours), you make sure that as one medication dips, the other is reaching its peak

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Hagen TM, et al

Without it, scientists cannot determine whether it is effective or safe in humans

This stability eliminates the need for protective carriers required by other growth factors, making both oral and injectable administration viable
