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By employing genome-scale metabolic reconstruction and biodomain enrichment, the authors identified a core set of 62 genes and specific metabolite-gene pairings, such as MTHFR-homocysteine and PDHA1-acetyl-CoA, that drive pathological metabolic flux

J., Harvey, S

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Nature, 542 (7639), 119123

It triggers lipolysis, breaking down stored fat and helping to shrink fat cells for smoother skin
