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Preclinical studies and clinical trials suggest that antioxidants, such as small thiol molecules (N-acetyl-L-cysteine and carbocysteine), antioxidant enzymes (glutathione peroxidases), activators of Nrf2-regulated antioxidant defense system (sulforaphane), and vitamins, for example, C, E, and D, enhance the endogenous antioxidant system and reduce oxidative stress

As an antioxidant, it is thought to reduce DNA damage

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In another PD mouse model, SF (282 mol/kg once in 2 days for 60 days) inhibited rotenone-induced deficiencies in locomotor activity and dopaminergic neuronal loss (83)