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Ethical statement The experimental design and reporting followed the ARRIVE guidelines to ensure transparency and reproducibility

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In this paper, we summarize the current knowledge on the ability of NAC to reduce drug-seeking behavior induced by psychostimulants, opioids, cannabinoids, nicotine, and alcohol in animals and humans

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The improvement in reproductive antioxidant defense systems may be due to the increase in reduced glutathione concentration and activities of glutathione peroxidase, catalase, and SOD enzymes (28, 61, 62), which protect the reproductive organs' defense systems against ROS attacks