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Front Neurosci 17:432

The ROS burst and mPTP opening cause an influx of water and solute that enhances mitochondrial swelling and the disruption of the outer membrane with the release of cytochrome C in the cytosol (90)

Ceramosides, a plant extract highly concentrated in phytoceramides, also help improve skin hydration, skin elasticity and moisture

These inconsistencies may reflect the differences in study methodologies and the need for more rigorous clinical trials with standardized endpoints and larger sample sizes
