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Chad Edwards and the team at Revolution Health & Wellness in Tulsa, OK are experts in non-surgical orthopedic therapies, including prolotherapy, PRP, and peptide therapy

A randomized, placebo-controlled trial in 559 elderly individuals with low serum levels of folate and vitamin B 12 and at increased risk of fracture evaluated the combined supplementation of very high doses of folic acid (5 mg/day) and vitamin B 12 (1.5 mg/day)

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It should not be used in pregnant or breastfeeding individuals, those with active cancer, or anyone with severe kidney or liver disease

To find out a specific mechanism, a comparison with the becaplermin (recombinant human plateletderived growth factor homodimer of B chains, PDGF-BB) was the focus of the two additional studies using excisional wounds in diabetic rats and mice (Figure 2) (Seveljevic-Jaran et al., 2006