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(e) Impact of environmental stress and diseases Aging, neurodegeneration (e.g., Alzheimer's disease), and inflammation induce epigenetic reprogramming in microglia, leading to subpopulations with pro-inflammatory or neuroprotective phenotypes (Gosselin et al., 2017

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also acknowledges support from NIH through grant numbers DK106993 (Type 1 Diabetes TrialNet) and CA215110

Kidney toxicity is a common side effect of some chemotherapy drugs such as cisplatin (Platinol), doxorubicin (Adriamycin), and oxaliplatin (Eloxatin) (Lahoti 2012

In OA, one of the core mechanisms of ferroptosis is the imbalance between lipid peroxidation and the antioxidant defense system
