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When to decrease dose Consider decreasing if: Persistent side effects that don't resolve Excellent results achieved and maintenance desired Budget constraints require conservation Stacking and wanting to optimize ratios Many researchers find they can reduce dose during maintenance phases after achieving initial goals during more intensive loading phases

On the other hand, we have recently identified a link between redox state and the microbiome 10

In resource-limited environments, AI can function as a decision support system, for example

Proc Natl Acad Sci United States America (2010) 107(5):2295300

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