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Evidence proving that chronic sub-label dosing yields similar long-term outcomes is lacking

SD, standard deviation

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In contrast, another study showed that the interaction between USP2 with TGFBR1 and TGFBR2 upon TGF stimulation was found to promote metastasis by facilitating the recruitment of SMAD2/3, essential components of the TGF signaling cascade in lung adenocarcinomas 45

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