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3 RGN-259 Phase 3 Trial in Neurotrophic Keratopathy Sosne et al., International Journal of Molecular Sciences (2022) This Phase 3 randomized, placebo-controlled, double-masked clinical trial evaluated topical 0.1% RGN-259 (full-length recombinant T4 ophthalmic solution) in patients with neurotrophic keratopathy

Trials with a Jadad score less than three were considered to have a high risk of bias [17]

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Note, portal hypertension, along with caval and intracranial hypertension and aortal hypotension, was regularly eliminated/attenuated [129,130,131,132,133,134,135,136,137,138,139,140,141,142]

What are the known side effects or adverse effects of subcutaneous (under the skin) cyanocobalamin (Vitamin B12) injections?
