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Description
Ferroptosis is mainly characterized by intracellular iron accumulation and lipid peroxidation, and is mainly related to intracellular iron accumulation, glutathione (GSH) depletion, glutathione peroxidase 4 (GPX4) inactivation, and increasing lipid peroxidation (Dixon et al

10.1007/s00401-007-0220-y Acta Neuropathol
Recently, population-based studies have revealed that ALS is an age-related disease similar to other age-associated neurodegenerative diseases like PD and AD [324]

Cell 56 , 13941407 (2021)

E., Greis P
