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showed that FOXO4 expression is upregulated in irradiated-induced senescent IMR90 cells and that the protein binds to p53, inhibiting the role of this last one in apoptosis induction
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Nerinetide (NA-1) is a polypeptide that interferes with postsynaptic density protein 95 (PSD-95) and reduces the interaction between PSD-95 and neuronal nitric oxide synthase, thereby reducing nitric oxide radical production and its mediated cell death [59]
