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On the other hand, vascular normalization therapies, where increases in VEGF signaling would promote blood vessel growth or enhanced function, demonstrate their own challenges most typically related to delivery kinetics, administration routes, and ability to evaluate clinical outcomes (259261)

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IGF-1 is responsible for many of the downstream effects associated with growth hormone, including: Muscle protein synthesis Recovery from exercise Bone remodeling Tissue repair Fat metabolism Cellular growth signaling Each peptide discussed below influences this pathway differently