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Actions of VIP in the body include: Vasodilation to assist in blood pressure regulation, GI tract epithelial cell secretion and blood flow increasing water and electrolytes in the GI tract, relaxation of intestinal smooth muscle, exerting a positive effect on hypothalamic kisspeptin neurons, hormone balancing, and aromatase inhibiting effect corrects estradiol, 25-OH Vitamin D, and testosterone in males, downregulation of th1 responses and controlling cytokine responses to restore immunoregulation, especially following infections by intracellular bacteria and viruses

Coadministration of trametinib and palbociclib radiosensitizes KRAS-mutant non-small cell lung cancers in vitro and in vivo

[DOI] [PubMed] [Google Scholar] Reily C., Stewart T

High oxidative stress can impair mitochondrial activity and damage cellular structures

doi: 10.1074/mcp.M113.029561 15 ChenY.SegersS.BlaserM