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Description
Future research should bridge the gap between nutritional neuroscience and clinical evidence, optimize overall dietary patterns, and investigate the mechanisms by which nutrients interact with the gut microbiota and central nervous systemultimately improving and preventing mental health through dietary interventions

Nuclear factor erythroid-derived 2-like 2 (NFE2L2, Nrf2) mediates exercise-induced mitochondrial biogenesis and the anti-oxidant response in mice

Endocrine Reviews , 28 (7), 778808
PMID 11169096

Complementarily, insulin can also bind to IGF-IR with a lower specificity than insulin receptor (Figure1)