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Description
Although generally mutations in TGF- receptors should decrease its downstream signaling, in LDS the direct effect is a nuclear accumulation of phosphorylated SMAD2 and increased connective tissue growth factor (59)
All these interventions offer promising avenues for modulating gut microbiota, reducing inflammation, improving lipid profiles, and ultimately mitigating cardiovascular risk
G., Kanwal, A., Kishore, A., Shenoy, R
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