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2018 May 17;19(7):56
IL-6 and TNF- levels are predictive of symptom severity and survival rates due to increased production of ROS and Reactive Nitrogen Species (RNS), with consequent oxidative stress-induced apoptosis [20, 54, 59]
Mitochondrial complex I proteins Ndufa3 and Ndufb3, apoptotic regulator Hax1, and complement protein C1qbp were down regulated in male APOE4 mice ( Figure 2B )
