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Treatment of A42-injected rats with an inhibitor of dipeptidylpeptidase-4, sitagliptin, together with quercetin, a flavonol from the flavonoid group of polyphenols, significantly diminished the level of A42 compared with either treatment alone but increased antioxidant protein levels (i.e., SOD, CAT) and the level of GSH and a diminution of histopathologically determined neuronal damage

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J Cell Biol 216(2):367377

The strength of this synergy depends on the reaction rates and the concentration of these antioxidants