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Studies show it can advance melatonin onset by about 31 minutes and mid-sleep time by nearly an hour

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SiesH.1991aOxidative stress: from basic research to clinical application.American Journal of Medicine.9131380002-9343 65

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This finding might be a sustainable solution to promote the patient's home-based self-assessment independently from the regular visits but also reinforce the clinician's ability to escort the patients into more conscious joint planning of the long-term disease management (Krupp, 1983a
