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These findings suggest that a large variety of degrading enzymes are involved in controlling ECM proteolytic activity and barrier integrity and that a deeper investigation of their functions is warranted to further our understanding of IBD pathophysiology

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It says the population of divers who reported feeling tired had lower DCS in DSL, most likely because they then dived more conservatively

The reduced PLP availability impairs key neurological enzymes

Gazendam RP, van Hamme JL, Tool ATJ, Hoogenboezem M, van den Berg JM, Prins JM, Vitkov L, van de Veerdonk FL, van den Berg TK, Roos D, et al.: Human Neutrophils Use Different Mechanisms To KillAspergillus fumigatusConidia and Hyphae: Evidence from Phagocyte Defects.J Immunol2016, 196:1272-1283 55