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In recent years there has been considerable interest in the therapeutic potential of L-carnitine and its acetylated derivative acetyl-L-carnitine (ALCAR) for neuroprotection in a number of disorders including hypoxia-ischemia, traumatic brain injury, Alzheimers disease and in conditions leading to central or peripheral nervous system injury

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Vitamin B supplementsespecially B12have some evidence supporting pain relief and modest improvements in nerve conduction

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For this reason, L-carnitine supplements are useful primarily to high-intensity athletes who value performance more than weight loss