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Biometals 17 , 6578 (2004)

Interestingly, it has been shown that GSH levels tend to increase due to glutamate-mediated excitatory activity (Tebartz Van Elst et al., 2014), and one of the hypotheses related to symptoms of ASD is the presence of an imbalance between excitatory neurotransmitter, glutamate, and one of the principal inhibitory transmitter, GABA

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A study in 2022 used this model to screen out a novel ALK5 inhibitor, TP-008, which reduced collagen deposition in mouse pulmonary fibrosis models by 70% (Luttens et al., 2025)

203218 Advances in Ocular Delivery Methods: Preclinical Studies Despite the intense and growing body of preclinical research focused on novel quercetin-based delivery systems, preclinical studies evaluating these nanoformulations remain extremely limited (Table 3)
