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Differential gene expression analysis of RNAseq of AD organoids compared to isogenic controls indicated activation of the ferroptotic pathway
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It also functions as a precursor to glutathione peroxidase, a key antioxidant enzyme, which protects against lipid peroxidation (fats turnin
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These data identify a clear association of humoral immunity with disease severity and point to immune mechanisms other than antibodies as relevant players in COVID-19 protection.
