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The Panel interpreted these data to indicate that for a particular patient, the balance between benefits and risks/burdens is uncertain or relatively equal and whether to use a particular treatment is a decision best made by the clinician who knows the patient with full consideration of the patient's prior treatment history, current quality of life, preferences and values

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doi: 10.1097/ALN.0000000000005006, PMID: [DOI] [PubMed] [Google Scholar] 53.Niikura K, Takahashi Y, Iino M, Funatsu Y, Matsuda R