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Parental nutrition, psychological stress, drug use/abuse, and the presence of environmental pollutants are all factors epigenetically affecting offspring genome

Inhibition of CPT1 decreases -synuclein concentration and attenuates normalized gene expression and inflammatory markers of reactive resident immune cells in the midbrain in PARK2 knockout mice exposed to rotenone Next, we speculated whether the rotenone exposure resulted in the establishment of key PD-like biochemical changes in the PARK2 knockout mice

Gene 585, 100103

10.1038/nchem.2133
