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This pathway begins with glutaminase-catalyzed production of ammonium and glutamate, which drives arginine biosynthesis and is subsequently sensed by CASTOR1, leading to persistent mTORC1 activation
Iron mediated oxidative stress plays an essential role in ferritin induced cell death
10.1074/jbc.M508361200 J
Abd-Allah SH, Khamis T, Samy W, Alsemeh AE, Abdullah DM, Hussein S
