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542 Although tau protein aggregation and beta-amyloid protein (A) accumulation play central roles in the pathophysiological hypothesis of AD, the potential role of metal overload, subsequent oxidative stress, and tissue damage cannot be ignored

Statements Author contributions XH: Conceptualization, Data curation, Formal Analysis, Investigation, Writing - original draft

Up to 20% of the population will experience hives at some point, and about 1% develop chronic urticaria

Lower levels of GSH were also observed in the substantia nigra of PD patients and the caudate nucleus of progressive supranuclear palsy (PSP) patients 16

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