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In particular, there are several mouse models with loss-of-function mutations in signaling through the GH/IGF-1 pathway which have revealed an extension in the animals lifespan

Journal Of Urology 2024, 212: 124-135

A., Mazloomi, M., Asemi, Z., & Esmaillzadeh, A

Together, the studies further indicate that HGH Fragment 176-191 may be beneficial to overweight or obese human patients, making it a potential candidate for further research [1]
