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PMC 3709007

The present study showed that PCOS was associated with increased expression of the p53 gene, a marker of apoptotic cell death in both kidney glomeruli and medullary tubules, and decreased expression of the Bcl2 gene, an anti-apoptotic marker in kidney glomeruli

Oxidized glutathione (GSSG) and GSH effects on intracellular calcium transients in glial cells at millimolar concentrations

662664 This intervention reverses the transcriptional silencing of Frataxin , decreases the production of aberrant early-terminated Frataxin transcripts, and increases both Frataxin mRNA and protein levels, presenting a promising therapeutic strategy for Friedreichs ataxia

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