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Long-term metformin therapy and vitamin B 12 deficiency: an association to bear in mind
doi: 10.1016/j.bmcl.2014.03.065
research shows no additional benefit above 1 mg daily Important: Doses above 1 mg (1,000 mcg) daily showed no additional metabolic benefits in clinical research
the caloric deficit converts that opportunity into actual results
In laboratory studies, inhibiting NNMT has been investigated for effects on cellular NAD+ levels and adipocyte (fat-cell) metabolism
