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Methods 40 , 3945 (1998)

In: Kagan VEQ, P

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In anterograde regulation, proteins encoded by the nuclear genome are transferred to the mitochondria to perform functions (71), while in retrograde regulation, the signal generated from mitochondria passes into the nucleus to induce gene expression, which occurs when mitochondrial homeostasis is interrupted by hypoxia or mutation in mtDNA, or mitochondrial Ca 2+ release (72, 73)

Int J Mol Sci 22(5) 2021 PMC7959288 Han SJ, Boyko EJ, Fujimoto WY, Kahn SE, Leonetti DL
