glutathione conjugation meaning of to a generic xenobiotic (X) via catalysis by Glutathione transporter as a target

V., Afonine, P

These robust in vitro and in vivo evidences collectively establish the indispensable physiological protective role of GPX4 in maintaining organismal redox homeostasis and defending against ferroptosis ( 2.3 Experimental evidence for ferroptosis in OA In recent years, as our understanding of ferroptosis has deepened, numerous basic and preclinical studies have accumulated compelling evidence supporting its active role in OA pathology

Thus, GABA from reactive astrocytes diminishes the spike probability of the perforant-path-to-dentate-granule-cell synapse, leading to impairment in synaptic plasticity and memory function

F., & Reboredo, F

They have proven to be effective in restoring endothelial function and augmenting angiogenesis in ischemic brain tissue (Peters, 2018)