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In participants with moderate-to-severe cognitive impairment (defined by MMSE), a larger improvement in cognitive performance was observed for donepezil and memantine, and their combination (donepezil +memantine), and these efficacy-related results are expected to also be reflected when a future study becomes available
Equal weights of both solutions were added together and mixed to form 16 mg/g STS in 0.5% HA in PBS

Yu L, Liu M, Xu S, et al

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