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Reduced lipogenesis and increased lipolysis in white adipose tissue Research demonstrated that NNMT inhibition by 5-Amino-1MQ reversed diet-induced obesity in mice, with significant reductions in body weight and white adipose tissue mass without affecting food intake

No extraneous vitamin B12 supplementation is necessary

Wolf, M

Acknowledgements This work was supported by the Intramural Research Program of the NIH/National Institute of Environmental Health Sciences 1Z01ES090079