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Who may benefit from taking vitamin B12 Vegans and vegetarians (B12 is found primarily in animal foods) People with low stomach acid or hypochlorhydria, which is common in older adults Those with medical conditions that reduce B12 absorption, including Crohns disease and celiac disease Those taking medications that impact B12 absorption, such as metformin and proton-pump inhibitors

Nutr., 77 : 459-464

D, possible rare cause

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Conclusions This case demonstrates that a deficiency in vitamin B12 can lead to severe macrocytic anemia and pancytopenia, both of which are significant yet treatable conditions