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[DOI] [PMC free article] [PubMed] [Google Scholar] 210.Baker D.J., Alimirah F., van Deursen J.M., Campisi J., Hildesheim J
10.1023/B:ANTO.0000020152.15440.65

Given the role of hydrogen peroxide in promoting both protective and apoptotic pathways, GPx-1 modulation of intracellular hydrogen peroxide flux will ultimately regulate both apoptotic and survival pathways
Subsequently, lipid peroxidation propagates via addition, hydrogen pumping, and fragmentation, and this process is repeated to form a chain reaction (Yu et al., 2015