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In the barrel-stave pore, the hydrophobic and hydrophilic arrangement of the lipids is maintained, whereas, in toroidal pores, the hydrophobic and hydrophilic arrangement of the bilayer is disrupted

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Simultaneously, it has been observed to modulate the expression of genes for proteoglycans and glycosaminoglycans (GAGs) like decorin, which are crucial for organizing collagen fibrils and maintaining tissue hydration in engineered skin equivalents