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F16 targets the mitochondrial stroma and induces mPTP opening, and its conjugates enhance cytotoxicity and aid tumor imaging, but are toxic to normal cells

Modulation of apoptosis by cytotoxic mediators and cell-survival molecules in Sjgren's syndrome

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Compared with traditional therapy modalities, nanoparticles improve the targeting efficiency of mitochondria, enhance the stability and bioavailability of therapeutics, and reduce the side effects on other non-target sites