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The absence of an organic anion transport system limits the usefulness of LLC-PK1 cell lines for studying nephrotoxic compounds, such as PCBD-NAC, that need active transport to enter the cells

While this guidance does not recommend any specific life cycle model or any specific technique or method, it does recommend that software validation and verification activities be conducted throughout the entire software life cycle

The brain is well adapted to neutralize oxidative injury by maintaining a high steady-state concentration of small-molecule intracellular antioxidants including glutathione in astrocytes and ascorbic acid in neurons

doi: 10.1016/j.redox.2023.102861 [DOI] [PMC free article] [PubMed] [Google Scholar] 148.Larsen EL, Kjr LK, Lundby-Christensen L, et al

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