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Iodine While iodine is an essential component of thyroid hormones, the selenium-containing iodothyronine deiodinases (DIOs) are enzymes required for the conversion of thyroxine (T 4 ) to the biologically active thyroid hormone, triiodothyronine (T 3 ) (see Function)

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We are grateful to the Key Laboratory of Craniocerebral Diseases for offering the experimental platform

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