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Cannabinoid receptors are also activated by endogenous ligands, the en-docannabinoids, a family of endogenous arachidonic acid derivatives, including N-arachidonylethanolamide (anandamide) and the 2-arachidonoylglycerol which is synthesized by the cell membrane (Sugiura et al., 2002)

The Anatomical Record

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On this basis, we posit that the therapeutic action of Erastin in EMS is critically mediated by these ROS-driven programs, and that pharmacologic suppression of mitophagy may further sensitize lesions to Erastin

These studies suggest that PGE2 suppresses antiviral CD8 + T cell function in both CD8 + T cell-intrinsic and -extrinsic manners (Fig