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After a treatment period of 3 months, to test the effectiveness of treatment as part of usual clinical care, vitamin B12 levels, activity meter, and questionnaires were repeated

Individuals With Malabsorption Conditions Certain medical conditions and medications can interfere with B12 absorption, including: Pernicious anemia (an autoimmune condition that impairs intrinsic factor production necessary for B12 absorption)[12]

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At the same time, it was agreed that symptoms affecting the central nervous system (mental function and neurological function), followed by those affecting the peripheral nervous system, are the most difficult symptoms to link to B12 deficiency (Figure 1), suggesting the need for more specific awareness in a primary medical care setting and an improvement in examination options

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